NeuroscienceJournal of NeurosciencePeer-reviewed
Effect of selective lesions of nucleus accumbens μ-opioid receptor-expressing cells on heroin self-administration in male and female rats: a study with novel Oprm1-Cre knock-in rats
Jennifer M. Bossert, Carlos A. Mejías-Aponte, Thomas L. Saunders…·Yavin Shaham
This study introduces a CRISPR-based Oprm1-Cre knock-in rat to investigate the role of nucleus accumbens MOR-expressing cells in heroin self-administration, finding sex-specific effects on acquisition and effort.
18 citations