Jonathan J. Chow

This study examines dopamine dynamics in the nucleus accumbens during positive and negative reinforcement in rats, finding distinct patterns for different reinforcer types and availability.

This study examines how morphine dependence and withdrawal affect operant social interaction in rats, finding that dependence reduces social interaction while withdrawal does not, and that pharmacological interventions targeting KOR, serotonin, or dopamine fail to reverse this effect.

This study introduces a CRISPR-based Oprm1-Cre knock-in rat to investigate the role of nucleus accumbens MOR-expressing cells in heroin self-administration, finding sex-specific effects on acquisition and effort.

This study shows that ventral subiculum neuronal ensembles are specifically involved in the incubation of oxycodone craving after voluntary abstinence, but not after forced abstinence or early abstinence.