Author

Ashley Townsel

Emory UniversityORCID 0000-0003-4513-6254Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Karmella Ann HaynesiD· 2 shared Maya JaffeiD· 2 shared Yifei WuiD· 2 shared Asia N. IngramiD· 1 shared Cara E. ShieldsiD· 1 shared Curtis James HenryiD· 1 shared Madison TiptoniD· 1 shared Melissa Lambeth KempiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Karmella Ann HaynesORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 8, 2026

Early Epigenetic and Metabolic Responses to the Adipocyte Secretome Reveal Stress-Adaptive States in Triple-Negative Breast Cancer

Ashley Townsel, Maya Jaffe, Shiyu He…·Karmella Ann Haynes

This study identifies how adipocyte secretome induces metabolic and epigenetic changes in TNBC cells, promoting stress-adaptive states through chromatin remodeling and metabolic reprogramming.

DOI 10.64898/2026.04.06.716548

humanbulk RNA-seq

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Synthetic BiologyACS Synthetic BiologyPeer-reviewedJul 8, 2025

Tet Transgene Activation is Disrupted in Lipogenic Triple Negative Breast Cancer Cells

Ashley Townsel, Yifei Wu, Maya Jaffe…·Karmella Ann Haynes

The paper shows that lipogenic metabolism in breast cancer cells disrupts Tet transgene activation by affecting chromatin remodeling substrates and cofactors.

3 citations

humanbulk RNA-seq

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