Author

Cara E. Shields

Emory UniversityORCID 0000-0002-3791-8259Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Karmella Ann HaynesiD· 2 shared Maya JaffeiD· 2 shared Ashley TownseliD· 1 shared Lauren HongiD· 1 shared Natecia L. WilliamsiD· 1 shared Yifei WuiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersSynthetic Biology

Karmella Ann HaynesORCID

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2 papers

Recent·Most cited

Tet Transgene Activation is Disrupted in Lipogenic Triple Negative Breast Cancer Cells

Ashley Townsel, Yifei Wu, Maya Jaffe, Cara E. Shields, Karmella Ann Haynes

The paper shows that lipogenic metabolism in breast cancer cells disrupts Tet transgene activation by affecting chromatin remodeling substrates and cofactors.

ACS Synthetic Biology · Jul 8, 2025Peer-reviewedSynthetic Biology

PIC recruitment by synthetic reader-actuators to polycomb-silenced genes blocks triple-negative breast cancer invasion

Natecia L. Williams, Lauren Hong, Maya Jaffe, Cara E. Shields, Karmella Ann Haynes

The paper develops a synthetic reader-actuator to activate silenced tumor suppressor genes in triple-negative breast cancer cells, reducing invasion and promoting apoptosis.

bioRxiv · Jan 23, 2023 · PreprintSynthetic Biology