Joel B. Dacks

The paper identifies the M6P pathway as ancient and widespread in eukaryotes, with functional diversification in Trichomonas vaginalis.

The paper uses comparative genomics and phylogenetic analysis to show eukaryotic Rad51 and DMC1 proteins diverge from asgardarchaeal RadA, supporting a model of eukaryogenesis involving mitochondrial acquisition and sex evolution.

This study reconstructs an ancestral GTPase and finds it localized to both Golgi and plasma membrane, a feature retained in modern Arf1 proteins.

The paper identifies Giardia intestinalis ARF GTPases and their regulators as key components of non-canonical endosomal compartments involved in vesicle formation and membrane fusion.

The paper investigates the prevalence and environmental abundance of the TSET membrane trafficking complex in five eukaryotic groups, showing its presence in photosynthetic organisms and its potential role in marine ecosystems.

This study identifies ArfR GTPases in Asgard archaea, showing they are ancestral to eukaryotic Arf family proteins and suggest early evolution of endomembrane systems.

This study identifies homology in lysosome-related organelle sorting machinery across eukaryotes, showing its origin predates the last eukaryotic common ancestor.

The paper studies the expansion of endomembrane rescue systems in parasitic Parabasalids by comparing them to their free-living sister lineage, identifying specific expansions and losses in Retromer and Retriever machinery.

The paper describes two new mantamonad species and provides transcriptomic and genomic data for one, offering insights into the CRuMs supergroup's evolutionary history.

This study presents the genome, RNA, and protein sequences of Euglena gracilis, revealing insights into its evolutionary history, gene regulation, and adaptability.