Paul T. Manna

This study identifies tetherin homodimerisation as essential for exosome tethering, showing that mutations affecting tetherin trafficking to ILVs have minimal impact on exosome retention.

This study shows that DNA-PK is a conserved DNA sensor in chickens that poxviruses evade by targeting with OPG020/OPG031 proteins, highlighting its role in innate immunity beyond mammals.

The paper identifies a missense mutation in VPS33A causing an attenuated juvenile form of mucopolysaccharidosis plus and shows potential therapeutic interventions.

The paper introduces a cloning-free CRISPR/Cas9 method for genomic editing in mammalian cells using PCR products, demonstrating efficient integration of tags into target loci.