Author

Aleksandr Bykov

St. Anna Children's Cancer Research InstituteORCID 0000-0003-4532-9865Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Barbara Sax· 1 shared Branka Radic-SarikasiD· 1 shared Danijela Kurija· 1 shared Florian HalbritteriD· 1 shared Gerhard Weber· 1 shared Heinrich KovariD· 1 shared Lukas KenneriD· 1 shared Maximilian O. Kauer· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Barbara Sax

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1 paper

Recent·Most cited

Cancer BiologyCell ReportsPeer-reviewedMar 1, 2025

YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1 mediated reprogramming of bone mesenchymal stem cells

Rahil Noorizadeh, Barbara Sax, Tahereh Javaheri…·Heinrich Kovar

The paper shows that IGF-1 reprograms bone mesenchymal stem cells in EWS::FLI1-mutant mice, leading to tumor formation, with Yap1 playing a central role, and suggests combined IGF-1R and YAP/TEAD inhibition as a potential treatment.

11 citations

mouseexperimental assay

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