Shazia Irshad

This paper develops a co-differentiation platform using human iPSCs to generate transplantable colonic tissue that mimics native mucosa and responds to biological signals.

The paper investigates how proximity of pre-mRNA 3' end processing and transcription termination affects gene expression in colorectal cancer, finding that closer proximity correlates with higher expression.

This study shows that probiotic treatment alleviates colitis in naked mole rats caused by Citrobacter braakii, offering a new model for studying inflammatory bowel disease.

Pathological epithelial GREM1 expression induces therapeutically reversible ectopic stem cell niches through stromal remodelling.