Karen Mruk

This study shows arsenic impairs human cardiac development by inhibiting cardiomyocyte differentiation and maturation, as demonstrated through stem cell and zebrafish models.

This paper develops an RNA-based chemogenetic method to induce tunable gene expression in zebrafish embryos and larvae, demonstrating time- and concentration-dependent control.

This study examines how the age of spinal cord injury in larval zebrafish affects regeneration and functional recovery, finding age-dependent differences in inflammatory responses and axonal regeneration.

This study shows that Vibrio fischeri, typically a mutualistic bacterium, can cause mortality in zebrafish embryos and Artemia nauplii via its type VI secretion system.

This study tests 4-AP's effect on SCI recovery in zebrafish, finding 10 M 4-AP improves swimming distance by 40% without axon regeneration.

This study compares three diets' effects on growth and spinal cord regeneration in larval zebrafish, finding significant differences in length and regeneration rates between live feed and commercial feeds.

This paper develops a method for targeted cell ablation in zebrafish embryos using optogenetic transcriptional control combined with genetically encoded toxins and cis-regulatory elements.