Molecular BiologybioRxivPreprint
SARS-CoV-2 protein Nsp1 alters actomyosin cytoskeleton and phenocopies arrhythmogenic cardiomyopathy-related PKP2 mutant
Cristina Márquez-López, Marta Roche-Molina, Nieves García-Quintáns…·Juan Antonio Bernal
The paper shows that SARS-CoV-2 Nsp1 protein mimics the effects of a PKP2 mutant by altering actomyosin cytoskeleton organization, suggesting a potential link between viral infection and ACM-like disease.
DOI 10.1101/2020.09.14.296178