Linda K. McEvoy

This paper introduces a non-contrast spin-labeling MRI technique to quantify CSF outflow in humans and finds that CSF flow metrics decline with age.

This study investigates the genetic and environmental factors influencing longitudinal predicted brain ageing (PBA) using MRI data from mid to late-age males, finding significant genetic heritability and stability over time.

This study demonstrates sex-dependent polygenic effects on Alzheimer’s disease progression by using polygenic hazard scores, showing stronger associations with clinical outcomes than traditional polygenic risk scores.

The paper identifies genetic variants associated with Alzheimer's disease and cardiovascular risk factors, showing lipid-related enrichment and pleiotropy beyond APOE.

This study evaluates whether a polygenic hazard score (PHS) can enhance the prediction of amyloid and tau deposition and progression to Alzheimer’s dementia when combined with biomarkers in nondemented individuals.

This paper develops and validates a polygenic hazard score to predict age-specific Alzheimer's disease risk using genetic data from multiple cohorts.