Mark Yarmarkovich

ImmunoVerse integrates RNA-Seq and immunopeptidomes to catalog 28,446 tumor-specific HLA-presented antigens across 21 cancers, including a splicing-derived PMEL peptide with T cell expansion support.

This paper introduces BayesTS, a Bayesian probabilistic score for tumor specificity to prioritize drug targets, demonstrating its effectiveness across multiple tissues and data types.