ImmunologyScience AdvancesPeer-reviewed
Human NLRP3 inflammasome activation leads to formation of condensate at the microtubule organizing center
Jue Wang, Man Wu, Le Xiao…·Grant J. Jensen
This study uses cryo-ET to visualize NLRP3 inflammasome condensates at the MTOC during activation, revealing structural changes and pyroptosis in macrophages.
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