Author

Bin Xu

Memorial Sloan Kettering Cancer CenterORCID 0000-0003-4638-9835Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Bin Xu1 paper · First Affiliated Hospital Zhejiang University

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Elisa de StanchinaiD· 2 shared Gnana Prakasam KrishnamoorthyiD· 2 shared James A. FaginiD· 2 shared Jeffrey A. KnaufiD· 2 shared Laura BoucaiiD· 2 shared Vera TiedjeiD· 2 shared Adrián Acuña-RuíziD· 1 shared Alan Loh HoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Elisa de StanchinaORCID

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2 papers

Recent·Most cited

Cancer BiologyJournal of Clinical InvestigationPeer-reviewedAug 19, 2025

Loss of tumor cell MHC Class II drives insensitivity of BRAF-mutant anaplastic thyroid cancers to MAPK inhibitors

Vera Tiedje, Jillian Greenberg, Tianyue Qin…·James A. Fagin

This study shows that loss of MHC Class II in BRAF-mutant anaplastic thyroid cancers leads to resistance to MAPK inhibitors by reducing CD4+ T-cell activation.

8 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyThe Journal of Experimental MedicinePeer-reviewedJan 14, 2025

RBM10 loss induces aberrant splicing of cytoskeletal and extracellular matrix mRNAs and promotes metastatic fitness.

Gnana Prakasam Krishnamoorthy, Anthony Robert Glover, Brian R. Untch…·James A. Fagin

This study shows that RBM10 loss causes aberrant splicing of cytoskeletal and ECM genes, leading to RAC1 activation and metastatic fitness in thyroid cancer.

13 citations

mousebulk RNA-seq

𝕏 PostBluesky