Francesca Storici

The paper investigates the role of RNase H types 1 and 2 in removing ribonucleotides from the genomes of two archaeal species using combined experimental and sequencing approaches.

The paper maps DNA-embedded ribonucleotides (rNMPs) across human cell types, revealing their non-random distribution and role as a novel epigenetic mark affecting gene expression.

The paper introduces rNMPID, a database that compiles rNMP-embedment data across species, providing insights into their genomic characteristics and potential roles in disease.

This study examines rNMP incorporation in AGS-ortholog yeast mutants, revealing differences in rNMP abundance and strand-specific patterns.

This study shows that transcript RNA facilitates DSB repair in human cells through NHEJ and MMEJ, promoting repair or mediating RNA-templated repair based on sequence complementarity.

The paper analyzes rNMP incorporation patterns around yeast ARSs to show differences in rNMP incorporation between leading and lagging strands, reflecting the labor division between Pol δ and Pol ε.

Ribose-Map provides a standardized toolkit for analyzing ribonucleotide sequencing data at single-nucleotide resolution, enabling identification of ribonucleotide incorporation patterns.

This study identifies co-expressed genes of RNASEH2A and reveals its involvement in DNA replication, DNA damage response, and cell cycle regulation, with increased expression in cancer cells.

The paper identifies a disproportionate incorporation of adenosine in mitochondrial and chloroplast DNA of Chlamydomonas reinhardtii compared to nuclear DNA, linked to elevated ATP levels.