Author

Ryan L. McCarthy

University of WashingtonORCID 0000-0003-4645-3526Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Adam BurtoniD· 1 shared Andrew KatznelsoniD· 1 shared Blake HernandeziD· 1 shared Holly Fahning· 1 shared Jingchao Zhang· 1 shared Kenneth S. ZaretiD· 1 shared Kylea Tapia· 1 shared Maria‐Elena Torres‐PadillaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperDevelopmental Biology

Adam BurtonORCID

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1 paper

Recent·Most cited

Developmental BiologyNature CommunicationsPeer-reviewedJul 30, 2026

ERH elicits cell lineage restriction in mammalian preimplantation development and differentiation from pluripotency via H3K9me3-heterochromatin

Andrew Katznelson, Blake Hernandez, Kylea Tapia…·Ryan L. McCarthy

This study shows ERH maintains H3K9me3 heterochromatin in mammalian cells, restricting lineage potential and repressing pluripotency genes during development and reprogramming.

3 citations

mousehuman

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