Author

Iván Plaza-Menacho

Spanish National Cancer Research CentreORCID 0000-0003-4666-9431Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ana Martín-HurtadoiD· 1 shared Eduardo ZarzuelaiD· 1 shared Federico GagoiD· 1 shared Fernando Garcı́aiD· 1 shared Inés G. MuñoziD· 1 shared Jana SáncheziD· 1 shared Jasminka BoskoviciD· 1 shared Javier MuñoziD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ana Martín-HurtadoORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMar 6, 2026

The oncogenic CCDC6-RET fusion product is a dual ATP and ADP-dependent kinase that functions via cis-phosphorylation

Ana Martín-Hurtado, Julia Contreras, Jana Sánchez…·Iván Plaza-Menacho

This study identifies CCDC6-RET as a dual ATP/ADP-dependent kinase with a unique dimeric structure and phosphorylation mechanism, revealing structural and functional determinants of its oncogenic activity.

1 citation

humanproteomics

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