Javier Muñoz

This study shows that GATA4 loss in Kras-mutant mice leads to PDAC without canonical precursor lesions, identifying a new lesion type and revealing GATA4's role in inflammatory programs.

This study shows that extracellular vesicles from senescent tumor cells are both necessary and sufficient to induce paracrine senescence in neighboring cells.

This study identifies CCDC6-RET as a dual ATP/ADP-dependent kinase with a unique dimeric structure and phosphorylation mechanism, revealing structural and functional determinants of its oncogenic activity.

The paper identifies RNA polymerase I as a target of Nse1's RING domain through ubiquitin proteomics, revealing a role in rDNA segregation.

The paper shows that Peroxiredoxin 2 is essential for the beneficial adaptive response to exercise-induced oxidative stress in C. elegans.

This study identifies PrimPol as a key player in ICL traverse, showing its primase activity is required for DNA damage tolerance and that its absence increases sensitivity to ICL-inducing drugs.

This study shows arginine-rich CPPs like (PR)n displace DNA- and RNA-binding factors, impairing nucleic acid processes and causing toxicity, similar to PROTAMINE's effects.