This study identifies the AAGAB pseudoGTPase domain as a novel protein-protein interaction module that interacts with AP1 and AP2 σ subunits, revealing a unique structural interface distinct from conventional GTPase interactions.

3 citations

humanstructural biology

𝕏 PostBluesky

Developmental BiologyGeneticsPeer-reviewedDec 22, 2020

The Drosophila SWI/SNF chromatin-remodeling complexes BAP and PBAP play separate roles in regulating growth and cell fate during regeneration

Yuan Tian, Rachel K. Smith-Bolton

This study identifies distinct roles of SWI/SNF chromatin-remodeling complexes PBAP and BAP in regulating regenerative growth and cell fate during Drosophila wing disc regeneration.

99 citations

Drosophilaexperimental assay

𝕏 PostBluesky

Developmental BiologyPLoS GeneticsPeer-reviewedJul 28, 2017

A Positive Feedback Loop Ensures Propagation of ROS Production and JNK Signaling Throughout Drosophila Tissue Regeneration

Sumbul Jawed Khan, Syeda Nayab Fatima Abidi, Andrea Skinner…·Rachel K. Smith-Bolton

The paper identifies a positive feedback loop between ROS production and JNK signaling during Drosophila wing disc regeneration using transcriptomic analysis.

79 citations

Drosophilabulk RNA-seq

𝕏 PostBluesky