S du Lac

Functional contributions of quantal and non-quantal hair cell synaptic transmission in the vestibular periphery

This study investigates the functional roles of quantal and non-quantal synaptic transmission from type I and II hair cells in mice, showing that non-quantal transmission can drive vestibular responses across a wide range of frequencies, while quantal transmission is essential for gravity detection.

Tau P301S Transgenic Mice Develop Gait and Eye Movement Impairments That Mimic Progressive Supranuclear Palsy

This study evaluates hTau.P301S mice for PSP-like features, finding motor and eye movement impairments linked to Tau pathology.

Modular output circuits of the fastigial nucleus mediate diverse motor and nonmotor functions of the cerebellar vermis

The paper identifies five distinct fastigial nucleus cell types in mice and shows they mediate diverse motor and nonmotor functions through modular synaptic connections.