Author

Paula M. Loria

Pfizer (United States)ORCID 0000-0003-4690-5991Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Allyn T. LondreganiD· 1 shared Austin HuangiD· 1 shared Bruce A. Maguire· 1 shared Chiachin Wilson Lee· 1 shared David R. Healy· 1 shared David W. PiotrowskiiD· 1 shared Donna N. Petersen· 1 shared Erik C. Ralph· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperSystems Biology

Allyn T. LondreganORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 12, 2026

Insight into the scaffolding function of USP18 from a high resolution cryo-EM structure of STAT2-USP18-ISG15 ternary complex

Kevin W. Huynh, Rachel Plumb, David R. Healy…·Masaya Yamaguchi

The paper determines the structure of the STAT2-USP18-ISG15 ternary complex using cryo-EM, revealing how USP18's scaffolding function suppresses IFN-I signaling by disrupting its enzymatic activity.

1 citation

protein structureexperimental assay

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Systems BiologyPLoS BiologyPeer-reviewedMar 21, 2017

A compound that directly and selectively stalls PCSK9 translation

Nathanael G. Lintner, Kim F. McClure, Donna N. Petersen…·Jamie H. D. Cate

A compound inhibits PCSK9 translation by stalling ribosomes at codon 34, reducing plasma PCSK9 and cholesterol in rats.

130 citationstop 2%

ratproteomics

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