Author
Lynne Regan
University of EdinburghORCID 0000-0003-4719-2495Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2025 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 24 mutual co-author links5 papers
Recent·Most cited
- Synthetic BiologyProtein SciencePeer-reviewed
Super-resolution imaging of proteins inside live mammalian cells with mLIVE-PAINT
Haresh Bhaskar, Zoe Gidden, Gurvir S. Virdi…·Mathew H. Horrocks
This study adapts the LIVE-PAINT method for live mammalian cells, demonstrating super-resolution imaging of two proteins in real time.
- Synthetic BiologybioRxivPreprint
Cell-free protein synthesis as a method to rapidly screen machine learning-directed protease variants
Ella Lucille Thornton, Jeremy T. Boyle, Nadanai Laohakunakorn, Lynne Regan
The paper uses cell-free protein synthesis to rapidly screen machine learning-directed protease variants and identifies improved kinetic properties in some variants.
- Synthetic BiologyProtein SciencePeer-reviewed
Live-cell super-resolution imaging of actin using LifeAct-14 with a PAINT-based approach
Haresh Bhaskar, Dirk‐Jan Kleinjan, Curran Oi…·Lynne Regan
The paper introduces direct-LIVE-PAINT, a method for nanoscopic imaging of protein structures in live cells, demonstrating its application to actin with sub-diffraction resolution.
13 citations - Synthetic BiologyCommunications BiologyPeer-reviewed
LIVE-PAINT: Super-Resolution Microscopy Inside Live Cells Using Reversible Peptide-Protein Interactions
Curran Oi, Zoe Gidden, Louise V. Holyoake…·Lynne Regan
LIVE-PAINT enables super-resolution imaging in live cells by using reversible peptide-protein interactions instead of direct fluorescent protein fusion.