Cancer BiologyThe EMBO JournalPeer-reviewed
GOT1 primes the cellular response to hypoxia by supporting glycolysis and HIF1α stabilisation
Fiona Grimm, Agustín Asuaje, Aakriti Jain…·Dimitrios Anastasiou
This study identifies GOT1 as a key factor in priming cells for hypoxic adaptation by enhancing glycolysis and HIF1α stabilization before full HIF1 activation.
16 citations