Author

Brent Eastman

Case Western Reserve UniversityORCID 0000-0003-4757-1209Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

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Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

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Evan S. DenerisiD· 1 shared Nobuko TabuchiiD· 1 shared William C. SpenceriD· 1 shared Xinrui L. ZhangiD· 1 shared

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2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperNeuroscience

Evan S. DenerisORCID

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1 paper

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedApr 1, 2025

LMX1B missense-perturbation of regulatory element footprints disrupts serotonergic forebrain axon arborization

Brent Eastman, Nobuko Tabuchi, Xinrui L. Zhang…·Evan S. Deneris

This study models human LMX1B missense mutations in mice, showing they disrupt serotonin axon arbor formation and regulatory element binding, affecting brain development and function.

2 citations

mouseDNA methylation

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