Author

Dushyant P. Purohit

James J. Peters VA Medical CenterORCID 0000-0003-4789-0373Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Research Focus:GWAS / association mapping· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Edward B. LeeiD· 2 shared John F. CraryiD· 2 shared Alan Edward RentoniD· 1 shared Alicia Casella· 1 shared Alison GoateiD· 1 shared Ana C. PereiraiD· 1 shared André CorveloiD· 1 shared Andrew F. TeichiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Edward B. LeeORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintApr 4, 2026

Single-Nuclei Transcriptomic Characterization of APOE4-Associated Alzheimer's Disease

Kaitlin E. Murtha, Anjalika Chongtham, W-m Song…·Ana C. Pereira

This study characterizes cell-type-specific transcriptomes across APOE genotypes in Alzheimer's disease using single-nuclei RNA sequencing, revealing APOE4-associated changes in excitatory neurons and microglia.

DOI 10.64898/2026.04.03.715591

humansnRNA-seq

𝕏 PostBluesky

NeuroscienceActa NeuropathologicaPeer-reviewedOct 31, 2021

Genome-wide association study and functional validation implicates JADE1 in tauopathy

Kurt W. Farrell, SoongHo Kim, Natalia Han…·John F. Crary

This study identifies JADE1 as a novel genetic factor in tauopathy through genome-wide association and functional validation in human and Drosophila models.

35 citationstop 5%

humanDrosophila

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NeurosciencebioRxivPreprintJan 8, 2021

The landscape of human brain immune response in patients with severe COVID-19

John F. Fullard, Hao-Chih Lee, Georgios Voloudakis…·Panos Roussos

The paper analyzes single-nucleus transcriptomes from brain regions of COVID-19 patients to show increased neuroinflammation and microglial transcriptome changes, without evidence of viral brain tropism.

1 citation

humanscRNA-seq

𝕏 PostBluesky