Cancer BiologybioRxivPreprint
An ERα-Dependent Hypoxia Response Defines EMT-Adjacent Tumour Regions and Suppresses the Pro-survival Effects of Amiloride in Estrogen Receptor-Positive Breast Cancer
Jodie R. Malcolm, Jack Stenning, Jacob Pope…·Andrew N. Holding
The paper identifies an ERα-dependent hypoxia response in ER+ breast cancer that influences gene expression and sensitivity to amiloride, linking hypoxia and ER signaling.
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