Katherine S. Bridge

This study identifies MBD1-L, an aberrantly spliced transcript in MDS, which drives epigenetic changes leading to myeloerythroid defects, and shows ASO-based targeting can restore erythroid differentiation.

This study identifies that HIF-1 activation by PIM1 in JAK2V617F-MPNs drives non-canonical transcription complex formation and disease progression.

The paper identifies an ERα-dependent hypoxia response in ER+ breast cancer that influences gene expression and sensitivity to amiloride, linking hypoxia and ER signaling.

DIANNeR improves detection of GR interactomes in normal tissues by integrating DIA, ion mobility, and library-free analysis, revealing context-specific networks and previously undetected interactions.

This study identifies RPLP1 and RPL27 as robust reference genes for RT-qPCR analysis of gene expression in hypoxic breast cancer cell lines.