Lakshmini Balachandar

The paper investigates how cortical microglia respond to TMEV infection by analyzing purinergic signaling, cytokine levels, and receptor expression across brain regions.

This study compares neuronal development and function in bipolar disorder with and without familial mitochondrial disease using iPSC-derived neurons.

The paper investigates microglial response to damage signals in a viral-induced mouse model of temporal lobe epilepsy, finding reduced P2ry12 expression and increased TNF-a during seizures and infection.

The paper evaluates AAV serotypes 1, 5, and 8 for transducing astrocytes in the rat brain cortex with an optogenetic construct and finds serotype 8 has the highest transduction efficiency.

This study develops a stochastic Ca2+ dynamics model to analyze optogenetic stimulation effects on astrocytes, identifying optimal light paradigms and parameters for enhancing Ca2+ spiking.