Author

Jaehyoung Choi

University of TorontoORCID 0000-0001-5848-1036Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ana C. AndreazzaiD· 3 shared Angela DuongiD· 2 shared Chiara C. BortolasciiD· 2 shared Dana El Soufi El SabbaghiD· 2 shared Ken R. WalderiD· 2 shared Michael BerkiD· 2 shared Peter Louis CarleniD· 2 shared A Bertrand· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Ana C. AndreazzaORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 22, 2025

From iPSCs to NPCs to cortical neurons: bioenergetic, neuronal, and calcium signaling phenotypes in bipolar disorder with and without familial mitochondrial disease

Dana El Soufi El Sabbagh, Jaehyoung Choi, Lakshmini Balachandar…·Ana C. Andreazza

This study compares neuronal development and function in bipolar disorder with and without familial mitochondrial disease using iPSC-derived neurons.

DOI 10.64898/2025.12.19.695603

humanbulk RNA-seq

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NeuroscienceTranslational PsychiatryPeer-reviewedAug 25, 2025

iPSC-Derived Cerebral Organoids Reveal Mitochondrial, Inflammatory and Neuronal Vulnerabilities in Bipolar Disorder

Dana El Soufi El Sabbagh, Alencar Kolinski Machado, Lauren Pappis…·Ana C. Andreazza

This study uses iPSC-derived cerebral organoids to show mitochondrial and inflammatory dysfunctions in bipolar disorder and tests potential therapeutic interventions.

19 citationstop 1%

humanexperimental assay

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NeurosciencePsychiatry ResearchPeer-reviewedJul 6, 2024

Mitochondrial Biomarkers and Metabolic Syndrome in Bipolar Disorder

Kassandra A. Zachos, Jaehyoung Choi, Ophélia Godin…·Nadja Kayser

This study investigates associations between mitochondrial metabolites and metabolic syndrome in bipolar disorder, finding significant links between lactate levels and metabolic syndrome markers, while cell-free mitochondrial DNA showed no association.

21 citationstop 2%

humanmetabolomics

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