Author

Tina Trachsel

Children's Hospital of PhiladelphiaORCID 0000-0003-4801-1350Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Jarad BeersiD· 2 shared Margaret C. Carroll· 2 shared Megha LaliD· 2 shared Melanie A. RuffneriD· 2 shared Ravi GautamiD· 2 shared Zoe Mrozek· 2 shared Amanda B. MuiriD· 1 shared Caitlin M. BurkiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Jarad BeersORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologyPediatric Allergy and ImmunologyPeer-reviewedFeb 27, 2026

Proton pump inhibitors modulate esophageal epithelial barrier function and crosstalk with eosinophils

Ravi Gautam, Megha Lal, Margaret C. Carroll…·Melanie A. Ruffner

This study shows that omeprazole modulates esophageal epithelial barrier function and reduces eosinophil activation in an IL-13-induced model of eosinophilic esophagitis.

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humanbulk RNA-seq

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ImmunologyCellular and Molecular Gastroenterology and HepatologyPeer-reviewedJan 1, 2025

Interferon-γ signaling in eosinophilic esophagitis has implications for epithelial barrier function and programmed cell death.

Megha Lal, Caitlin M. Burk, Ravi Gautam…·Melanie A. Ruffner

This study investigates interferon-γ signaling in eosinophilic esophagitis, showing its impact on epithelial barrier function and apoptosis in esophageal epithelial cells.

20 citationstop 1%

humanscRNA-seq

𝕏 PostBluesky