Author

Zoe Mrozek

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Jarad BeersiD· 2 shared Megha LaliD· 2 shared Melanie A. RuffneriD· 2 shared Ravi GautamiD· 2 shared Alyssa BaccarellaiD· 1 shared Amanda B. MuiriD· 1 shared Ann Semeao· 1 shared Ezuka Ogbolu· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Jarad BeersORCID

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Author profile →

2 papers

Recent·Most cited

Systemic Analysis of Patient Derived Esophageal Epithelial Organoid Model Reveals Cell State Heterogeneity and Conservation of Differentiation Hierarchy

Alyssa Baccarella, Yusen Zhou, Tatiana A. Karakasheva, Ravi Gautam, Megha Lal, Jarad Beers, Zoe Mrozek, Ann Semeao, Leena Mirchandani, Ryugo Teranishi, Takefumi Itami, Kanak Kennedy, Mark Mahon, Ezuka Ogbolu, Judith R. Kelsen, , Melanie A. Ruffner

The paper uses scRNA-seq to compare IL-13-treated esophageal organoids with EoE biopsies, revealing shared cell state heterogeneity and differentiation hierarchy dysregulation.

bioRxiv · Oct 30, 2026 · PreprintCell Biology

Proton pump inhibitors modulate esophageal epithelial barrier function and crosstalk with eosinophils

Ravi Gautam, Megha Lal, Margaret C. Carroll, Zoe Mrozek, Tina Trachsel, Jarad Beers, Melanie A. Ruffner

This study shows that omeprazole modulates esophageal epithelial barrier function and reduces eosinophil activation in an IL-13-induced model of eosinophilic esophagitis.

Pediatric Allergy and Immunology · Feb 27, 2026Peer-reviewedImmunology