Author

Yoko Kosaka

Oregon Health & Science UniversityORCID 0000-0003-4811-099XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Evan F. LindiD· 2 shared Jessica S. Mulkey· 2 shared Aaron ProdeusiD· 1 shared Allie Luther· 1 shared Birgit C. SchultesiD· 1 shared Brett A. DavisiD· 1 shared Chiara BoniniiD· 1 shared Cora E. Layman· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSynthetic Biology

Evan F. LindORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintJul 28, 2026

Engineering antigen-driven co-stimulation and T helper cell activity into TCR-T cells with CD8-41BB fusion receptors enhances anti-tumor activity

Ivy Dutta, Justin Oh, Liz Cam…·Aaron Prodeus

This paper enhances TCR-T cell anti-tumor activity by engineering CD8-41BB fusion receptors, improving CD4+ and CD8+ T cell functions and tumor regression in mouse models.

DOI 10.64898/2026.07.27.739613

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintJun 17, 2026

Azacytidine restores T cell function in AML by modulating DNA methylation

Ravina Pandita, Yoko Kosaka, Jessica S. Mulkey…·Evan F. Lind

This study shows azacytidine improves T cell function in AML by altering DNA methylation and reducing T cell exhaustion.

DOI 10.64898/2026.06.14.732148

mouseDNA methylation

𝕏 PostBluesky