Brett A. Davis

This study shows maternal obesity causes sex-dependent epigenetic and transcriptomic changes in offspring hearts, leading to sex-specific cardiac remodeling and disease risk.

This study shows that early-life wildfire smoke exposure in rhesus macaques leads to long-term immune and epigenetic changes, including altered cytokine responses and accelerated epigenetic aging.

The paper identifies differentially expressed genes in the parabrachial nucleus of two Xenopus frog species, linking them to vocal pattern differences.

This study shows azacytidine improves T cell function in AML by altering DNA methylation and reducing T cell exhaustion.

This study identifies astrocyte reactivity in the central amygdala due to ethanol dependence through multi-omics analysis in mice, revealing adaptive and maladaptive changes in neuroimmune and cytoskeletal pathways.

This study identifies epigenetic and transcriptomic changes in the hippocampus and blood of an Alzheimer's mouse model before amyloidosis onset, suggesting blood methylation as a potential biomarker.

This study shows that bisphenol A inhibits cancer-protective ESR1 signaling in human liver cells at environmentally relevant doses, suggesting it promotes liver cancer.

This study identifies astrocyte-specific gene and pathway changes in the nucleus accumbens during alcohol dependence using RNA-Seq and TRAP, revealing distinct immune activation patterns compared to ethanol drinking.

The paper shows that ethanol inhibits astrocyte translation of Chpf2 and Chsy1, reducing CS-GAGs and increasing dendritic arborization in hippocampal neurons.

The paper investigates molecular mechanisms of aneuploidy during early mammalian embryogenesis, revealing the role of mitotic checkpoint proteins and chromosomal mis-segregation in developmental arrest.