Yu Usami

This study identifies TMEM2 as a regulator of hyaluronan turnover in articular cartilage, showing its role in maintaining ECM integrity during osteoarthritis progression.

The paper identifies a Wnt-responsive fibrocartilage progenitor system that coordinates postnatal mandibular condylar cartilage growth through Foxm1-dependent proliferation and suppression of TGF-β-driven chondrogenic differentiation.

This paper demonstrates that retinoid-impregnated nanoparticles can modulate bone growth by selectively targeting growth plates in mice, leading to localized changes in tibia length and angulation.

This study shows that nutrient availability regulates chondroprogenitor accumulation and differentiation in the growth plate, with IGF-1 promoting differentiation after nutrient recovery.