Daniel Beckett

This study identifies how Plasmodium tubulin adaptations lead to distinct microtubule structures, mechanics, and drug susceptibility compared to mammalian microtubules.

This study uses multiscale modeling to show that microtubule plus-end tips bend outward into curved structures regardless of GTP hydrolysis state, challenging existing models linking curvature to nucleotide state.

This paper uses an equation-free method to accelerate all-atom simulations of microtubule tips, revealing structural differences between GDP- and GTP-bound states.