Author

Aodán Laighneach

Ollscoil na Gaillimhe – University of GalwayORCID 0000-0003-4853-8953Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Organism:human· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Derek W. MorrisiD· 4 shared Gary J DonohoeiD· 3 shared Dara M. CannoniD· 2 shared Declan Patrick McKernaniD· 2 shared Emma CorleyiD· 2 shared John P. KellyiD· 2 shared Laurena HolleraniD· 2 shared Aiden Peter CorviniD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersGenetic & Genomic Medicine

Derek W. MorrisORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 19, 2026

Altered Frontoparietal, Temporal and Sensorimotor Structure-Function Coupling and Its Genetic Underpinnings in Bipolar Disorder

Shir Dahan, Lara Ressin, Vilte Baltramonaityte…·Dara M. Cannon

This study identifies altered structure-function coupling in bipolar disorder and links these changes to genetic loci involved in neuronal development and signaling.

DOI 10.64898/2025.12.18.695223

humanstatistical model

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Genetic & Genomic MedicinemedRxivPreprintMay 15, 2025

Genome-wide association studies of social participation and occupational engagement in the UK Biobank

Evie Doherty, Aodán Laighneach, Mia Casburn…·Derek W. Morris

This study identifies genetic loci associated with social participation and occupational engagement using UK Biobank data, finding genetic correlations with neuropsychiatric disorders and socioeconomic factors.

1 citation

humanGWAS summary statistics

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NeuroscienceMolecular CellPeer-reviewedJan 21, 2024

SATB2 organizes the 3D genome architecture of cognition in cortical neurons

Nico Wahl, Sergio Espeso‐Gil, Paola Chietera…·Galina Apostolova

The paper shows SATB2 influences 3D genome structure in cortical neurons, affecting gene expression and cognitive-related functions.

25 citations

humanChIP-seq

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GenomicsPLoS ONEPeer-reviewedDec 21, 2023

Social isolation-induced transcriptomic changes in mouse hippocampus impact the synapse and show convergence with human genetic risk for neurodevelopmental phenotypes

Aodán Laighneach, John P. Kelly, Lieve Desbonnet…·Derek W. Morris

This study identifies transcriptomic changes in mouse hippocampus due to social isolation and links them to human genetic risk factors for neurodevelopmental disorders.

5 citations

mousebulk RNA-seq

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GeneticsbioRxivPreprintDec 7, 2023

Direct targets of MEF2C are enriched for genes associated with schizophrenia and cognitive function and are involved in neurogenesis and mitochondrial function

Deema Ali, Aodán Laighneach, Emma Corley…·Derek W. Morris

The paper identifies MEF2C direct target genes enriched for schizophrenia and cognitive function genes, showing their involvement in neurogenesis and mitochondrial function.

DOI 10.1101/2023.12.07.570529

humanbulk RNA-seq

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