Author

Leonidas G. Koniaris

Oregon Health & Science UniversityORCID 0000-0003-4864-6380Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Teresa A. ZimmersiD· 3 shared Alexander G. RoblingiD· 1 shared Andris KronbergsiD· 1 shared April M. Hoggatt· 1 shared Ashok Narasimhan· 1 shared Brittany R. CountsiD· 1 shared Clark D. Wells· 1 shared Daniel E. I. Schloss· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

Teresa A. ZimmersORCID

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Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 1, 2025

Pancreatic Cancer Induces Population-Specific Switching of Myosin Isoforms and Discrete Activation of Cachexia Genes in Skeletal Muscle Myocytes

Brittany R. Counts, Sephora Jean, Omnia U. Gaafer…·Teresa A. Zimmers

This study identifies population-specific transcriptional changes in skeletal muscle myonuclei during pancreatic cancer cachexia, revealing distinct gene activation patterns rather than uniform upregulation of cachexia mediators.

DOI 10.1101/2025.09.01.673500

humanscRNA-seq

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PhysiologybioRxivPreprintApr 1, 2025

Hepatic Yap1 activates systemic catabolism and muscle loss during organ repair: evidence for a liver-derived common mechanism with cancer cachexia.

Tewfik Hamidi, Yanlin Jiang, Tyler P. Robinson…·Leonidas G. Koniaris

This study shows that liver-derived Yap1 activation during organ repair induces systemic catabolism and muscle loss, similar to cancer cachexia.

DOI 10.1101/2025.04.01.646698

mousebulk RNA-seq

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Cancer BiologybioRxivPreprintJun 30, 2018

Identification of circulating protein biomarkers for pancreatic cancer cachexia

Safi Shahda, Ashok Narasimhan, Joshua Kays…·Teresa A. Zimmers

This study identifies circulating protein biomarkers associated with pancreatic cancer cachexia using serum samples and correlates them with clinical measures.

DOI 10.1101/359661

humanproteomics

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