Hanwen Xu

Capricorn enhances low-coverage Hi-C contact matrices using a multi-view diffusion model to improve loop detection accuracy across cell lines and chromosomes.

This paper demonstrates how large language models can generate malicious abstracts to poison scientific knowledge graphs and manipulate downstream biological applications.

ActFound is a foundation model for bioactivity prediction trained on 2.3 million compounds and 50,869 assays, showing strong generalization and performance comparable to FEP+(OPLS4).

Gemini integrates hundreds of gene networks using memory-efficient high-order pooling, improving protein function prediction performance.

PccGEO designs functional genetic elements using a knowledge-constrained deep learning model, achieving high success rates in promoter design for E. coli.

ARIC estimates cell type proportions from bulk gene expression or DNA methylation data, showing accuracy in both data types.