Zixuan Liu

Nanoscale Optical Imaging, Reconstruction, and Spatial Analysis of Whole Mouse Glomeruli

The paper develops a pipeline for high-resolution imaging and analysis of whole mouse glomeruli, revealing novel aging and disease-related phenotypes.

Generative steering to adapt proteins beyond native biological contexts

ProVADA adapts proteins to non-native contexts by steering a pretrained generator while preserving function, successfully converting renin and deimmunizing antibodies.

Pisces: A multi-modal data augmentation approach for drug combination synergy prediction

Pisces enhances drug combination synergy prediction by generating 64 augmented views per drug pair, achieving state-of-the-art results across multiple prediction tasks.

Enhancing Hi-C contact matrices for loop detection with Capricorn, a multi-view diffusion model

Capricorn enhances low-coverage Hi-C contact matrices using a multi-view diffusion model to improve loop detection accuracy across cell lines and chromosomes.

Poisoning scientific knowledge using large language models

This paper demonstrates how large language models can generate malicious abstracts to poison scientific knowledge graphs and manipulate downstream biological applications.