Bin Feng

This study shows that colorectal tissue and its nerve fibers exhibit auxetic behavior during circumferential stretching, with measurable deformation at both macro and micro scales.

This study compares activation thresholds of C-fiber afferents using dorsal root ganglion and peripheral nerve stimulation, finding DRG stimulation activates a larger proportion of C-fibers with lower thresholds.

The paper develops methods to mechanically test and analyze nerve fiber deformation in the myenteric plexus of mouse colorectum under loading, providing tools for quantitative stretch ratio calculations.

This paper demonstrates that temporal interference stimulation (TIS) can selectively block C-fiber transmission in dorsal root ganglia, reducing visceral pain in mice.

The paper characterizes VGLUT2-positive enteric neurons in mice, revealing their unique morphology, gene expression, and functional activation via colorectal stretch.

The paper identifies Avpr1a as a novel candidate gene for chronic visceral pain through genomic and functional analyses in mouse models and human patients.

ActFound is a foundation model for bioactivity prediction trained on 2.3 million compounds and 50,869 assays, showing strong generalization and performance comparable to FEP+(OPLS4).

The paper develops an artifact removal algorithm for neural recordings, improving signal-to-noise ratio by 20-40 dB across multiple stimulation scenarios.