Jaime Kulisevsky

The paper develops URSA, a method to quantify DNA repair activity at the CAG repeat tract in HD, showing it correlates with somatic instability and can be measured rapidly in blood cells.

The paper uses connectome-based brain fingerprinting to identify early cognitive decline markers in Parkinson's patients with minor hallucinations using resting-state fMRI.

The paper identifies distinct plasmatic immune extracellular vesicle profiles associated with different stages of neurodegenerative proteinopathies, with the highest diagnostic utility for prodromal REM sleep behavior disorder.

The paper identifies small RNAs in plasma extracellular vesicles as biomarkers for premanifest changes in Huntington's disease, showing their association with cognitive performance and longitudinal progression.

The paper performs a GWAS on PSP in the Iberian population, replicates known risk variants, and identifies a novel locus in NFASC/CNTN2 associated with oligodendrocyte and myelination processes.

The paper investigates if minor hallucinations in Parkinson's disease are linked to frontal theta oscillations and cognitive decline, finding a correlation between these factors and later cognitive impairment.

The paper investigates neural signatures of predictive language processing in Parkinson's disease patients with and without mild cognitive impairment using ERP measurements.

This study uses robotics to induce hallucinations in Parkinson's disease patients and identifies a disrupted neural network associated with sensorimotor hallucinations.

This study conducts a GWAS of Parkinson disease in Spain, identifies a novel population-specific signal at PARK2 associated with age-at-onset, and highlights genetic substructure for future fine-mapping.