NeuroscienceJournal of NeurochemistryPeer-reviewed
Excitotoxic glutamate levels cause the secretion of resident endoplasmic reticulum proteins
Amanda M. Dossat, Kathleen A. Trychta, Elliot J. Glotfelty…·Brandon K. Harvey
The paper shows that glutamate receptor activation causes ER Ca2+ depletion, leading to secretion of ER resident proteins and disrupting proteostasis during excitotoxicity.
10 citations