Deepro Banerjee

The paper quantifies how genetic mutations affect enhancer activity and gene expression using a novel method and identifies TF-specific regulatory programs and enhancer-gene relationships.

The paper examines how modifier variants affect clinical outcomes in individuals with primary disease variants, showing context-dependent phenotypic associations and synergistic interactions.

The paper develops a framework to study variable expressivity in genetic disorders using 16p12.1 deletion models, showing how genetic background and secondary variants influence gene expression and phenotypes.

The paper identifies transcriptome changes in the medial prefrontal cortex of stress-resilient mice with disinhibited SST neurons, showing bidirectional gene expression shifts linked to behavioral resilience and sex-specific mechanisms.

This study identifies 13 obesity-related genes, including five novel ones, through a cross-ancestry analysis of BMI in 839,110 individuals.

Flynotyper 2.0 improves upon its predecessor by enhancing computer vision and streamlining analysis for high-throughput Drosophila eye phenotype quantification.

The paper examines how assortative mating and parental genetic relatedness influence the pathogenicity of variably expressive variants in neurodevelopmental disorders.

This paper identifies critical steps and QC checkpoints for reproducibility of STARR-seq assays and provides guidelines for experimental design and analysis pipelines.

EnZymClass predicts plant acyl-ACP thioesterase substrate specificity using ensemble learning, achieving high accuracy and outperforming existing methods.