Author

Paige Whyte‐Fagundes

University of California, San FranciscoORCID 0000-0003-4878-9955Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:zebrafish· 3 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Scott C. BarabaniD· 2 shared A Carroll· 1 shared A Vance· 1 shared Aline Frick· 1 shared Catherine Manukyan· 1 shared Christiane Zoidl· 1 shared Daria TaskinaiD· 1 shared F Figueroa· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPharmacology & Toxicology

Scott C. BarabanORCID

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3 papers

Recent·Most cited

Pharmacology & ToxicologyPharmacology Research & PerspectivesPeer-reviewedJun 1, 2026

Virtual screening and zebrafish phenotype-based evaluation argues against repurposing 4-phenylbutyrate for STXBP1-relateddisorders

Aline Frick, Paige Whyte‐Fagundes, Scott C. Baraban

The paper evaluates 4-PBA and its analogs for treating STXBP1 disorders using zebrafish models and finds no rescue of movement or seizure phenotypes.

DOI 10.1002/prp2.70285

zebrafishexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 11, 2023

Testing of putative antiseizure drugs in a preclinical Dravet syndrome zebrafish model

Paige Whyte‐Fagundes, A Vance, A Carroll…·Scott C. Baraban

The paper tests nine putative antiseizure drugs in a scn1lab zebrafish model of Dravet syndrome, finding none significantly suppress seizures in electrophysiology assays.

1 citation

zebrafishexperimental assay

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NeuroscienceCommunications BiologyPeer-reviewedMay 18, 2022

Panx1 channels promote both anti- and pro-seizure-like activities in the zebrafish via p2rx7 receptors and ATP signaling

Paige Whyte‐Fagundes, Daria Taskina, Nickie Safarian…·Georg Zoidl

This study shows that Panx1 channels in zebrafish have both anti- and pro-seizure effects through p2rx7 receptors and ATP signaling.

14 citations

zebrafishbulk RNA-seq

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