Author

Ferdinando Insalata

Imperial College LondonORCID 0000-0003-4881-8138Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scATAC-seq· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Nick S. JonesiD· 2 shared Alistair P. GreeniD· 1 shared Becca AsquithiD· 1 shared Hanne Hoitzing· 1 shared Hetvi JethwaniiD· 1 shared Juvid AryamaniD· 1 shared Kamal Khairudin SukandariD· 1 shared Katherine R. SchoniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenomics

Nick S. JonesORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 20, 2026

Large-scale single-cell mapping of concealed mitochondrial ageing

Hetvi Jethwani, Kamal Khairudin Sukandar, Alistair P. Green…·Nick S. Jones

The paper maps concealed mitochondrial DNA mutations across 2.7 million cells from 311 individuals, finding that low-prevalence mutations accumulate with age and predict human age.

DOI 10.64898/2026.07.14.738425

humanscATAC-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintSep 1, 2020

Stochastic survival of the densest and mitochondrial DNA clonal expansion in ageing

Ferdinando Insalata, Hanne Hoitzing, Juvid Aryaman, Nick S. Jones

This paper presents a spatial model showing that mitochondrial DNA mutations expand through stochastic survival of the densest and noise, not replicative advantage, explaining ageing-related clonal expansion.

1 citation

statistical model

𝕏 PostBluesky