Eric Barklis

This study develops domain-specific nanobodies that inhibit SARS-CoV-2 infection by disrupting N protein phase separation and replication.

The paper investigates factors regulating HIV-1 fusion in reverse, finding that Env activity depends on cell surface levels, is inhibited by a fusion inhibitor, and is influenced by lipid membrane composition.

This paper shows that lentiviruses decorated with a nanobody targeting SARS-CoV-2 Spike selectively infect Spike-expressing cells and can deliver cargo to infected cells.