BioengineeringThe CRISPR JournalPeer-reviewed
Efficient Generation of SOCS2 Knock-out Sheep by Electroporation of CRISPR-Cas9 Ribonucleoprotein Complex with Dual-sgRNAs.
Ahmed Kasim Mahdi, Devon S. Fitzpatrick, Darren E. Hagen…·Pablo J. Ross
This study generates SOCS2 knock-out sheep using CRISPR-Cas9 ribonucleoprotein electroporation, resulting in compound heterozygotes with large deletions and trace SOCS2 expression.