Author

Nicholas Werry

Ontario Veterinary CollegeORCID 0000-0002-7014-8911Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alison Louise Van EenennaamiD· 2 shared Bret Roberts McNabbiD· 2 shared Devon S. FitzpatrickiD· 2 shared Tara Marie Urbano· 2 shared Ahmed Kasim MahdiiD· 1 shared Austin R Brown· 1 shared Craig D. C. BaileyiD· 1 shared Darren E. HageniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Alison Louise Van EenennaamORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Large Animal Model of Heritable Pulmonary Arterial Hypertension UsingGene-edited BMPR2 Sheep

Sanjeev A. Datar, Nicholas Werry, Austin R Brown, Devon S. Fitzpatrick, Oluwafemi Falade, Josephine F. Trott, Rachel Hutchings, Elena K. Amin, Jessica M. Morgan, Hythem M. Nawaytou, Gail H. Deutsch, Eric G. Johnson, Omar Gonzáles-Viera, Thomas Bishop, Tara Marie Urbano, , Alison Louise Van Eenennaam

This paper develops a gene-edited ovine model of heritable pulmonary arterial hypertension to study BMPR2 mutations and their pathophysiology.

JCI Insight · Jul 14, 2026Peer-reviewedMolecular Biology

Efficient Generation of SOCS2 Knock-out Sheep by Electroporation of CRISPR-Cas9 Ribonucleoprotein Complex with Dual-sgRNAs.

Ahmed Kasim Mahdi, Devon S. Fitzpatrick, Darren E. Hagen, Bret Roberts McNabb, Tara Marie Urbano, William M. Muir, Nicholas Werry, Alison Louise Van Eenennaam, J. F. Medrano, Pablo J. Ross

This study generates SOCS2 knock-out sheep using CRISPR-Cas9 ribonucleoprotein electroporation, resulting in compound heterozygotes with large deletions and trace SOCS2 expression.

The CRISPR Journal · Jan 14, 2025Peer-reviewedBioengineering

Human Cerebral Spheroids Undergo Activity Dependent Changes In Cellular Composition And MicroRNA Expression

Thomas Parmentier, Fiona James, Elizabeth Hewitson, Craig D. C. Bailey, Nicholas Werry, Steven D. Sheridan, Roy H. Perlis, Melissa L. Perreault, Luís Gaitero, Jasmin Lalonde, Jonathan LaMarre

The paper shows that increasing neuronal activity in human cerebral spheroids increases new neurons and decreases new glial cells, with reduced miR-135a expression.

Scientific Reports · Jun 1, 2022Peer-reviewedNeuroscience