Author
University of California, RiversideORCID 0000-0003-4964-7713Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Chinmai Pindi, Mohd Ahsan, Souvik Sinha, Giulia Palermo
This study uses deep learning and simulations to uncover the molecular mechanisms of TnsC filament assembly in a CRISPR-associated transposon.
Amun C. Patel, Souvik Sinha, Pablo Ricardo Arantes, Giulia Palermo
This study reveals the conformational dynamics of the Cas8 protein in the Cascade-TniQ complex, showing how it transitions between open and closed states to facilitate DNA binding and transposition.
Adrian Moises Molina Vargas, Souvik Sinha, Raven M. Osborn…·Mitchell R. O’Connell
This paper develops new CRISPR-Cas13a variants and crRNA design strategies to improve RNA-detection specificity, achieving better discrimination of SARS-CoV-2 strains.