Author

Dwight J. Hardy

University of Rochester Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:clustering· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adel MalekiD· 1 shared Adrian Moises Molina VargasiD· 1 shared Amun C. PateliD· 1 shared Andrew CameroniD· 1 shared Archibald S. PerkinsiD· 1 shared Brenda L. TesiniiD· 1 shared Giulia PalermoiD· 1 shared Heba H. MostafaiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

Adel MalekORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

New design strategies for ultra-specific CRISPR-Cas13a-based RNA-diagnostic tools with single-nucleotide mismatch sensitivity

Adrian Moises Molina Vargas, Souvik Sinha, Raven M. Osborn, Pablo R Arantes, Amun C. Patel, Stephen Dewhurst, Dwight J. Hardy, Andrew Cameron, Giulia Palermo, Mitchell R. O’Connell

This paper develops new CRISPR-Cas13a variants and crRNA design strategies to improve RNA-detection specificity, achieving better discrimination of SARS-CoV-2 strains.

Nucleic Acids Research · Nov 9, 2023Peer-reviewedMolecular Biology

Next-generation sequencing based hospital outbreak investigation yields insight into Klebsiella aerogenes population structure and determinants of carbapenem resistance and virulence

Adel Malek, Kelly A. McGlynn, Samantha M. Taffner, Lynn Fine, Brenda L. Tesini, Jun Wang, Heba H. Mostafa, Sharon Petry, Archibald S. Perkins, PAUL S. GRAMAN, Dwight J. Hardy, Nicole Pecora

The paper uses whole-genome sequencing to investigate a hospital outbreak of carbapenem-resistant Klebsiella aerogenes, identifying genetic factors contributing to resistance and virulence.

Antimicrobial Agents and Chemotherapy · Mar 26, 2019Peer-reviewedGenomics